Molecular basis of human disease -- Evidence-based medicine, quality of life, and the cost of medicine -- Structure and function of the normal heart and blood vessels -- Evaluation of the patient with cardiovascular disease -- Diagnostic tests and procedures in the patient with cardiovascular disease -- Heart failure and cardiomyopathy -- Congenital heart disease -- Acquired valvular heart disease -- Coronary heart disease -- Cardiac arrhythmias -- Pericardial and myocardial disease -- Other cardiac topics -- Vascular diseases and hypertension -- The lung in health and disease -- General approach to patients with respiratory disorders -- Evaluating lung structure and function -- Obstructive lung diseases -- Interstitial lung diseases -- Pulmonary vascular disease -- Disorders of respiratory control -- Disorders of the pleura, mediastinum, and chest wall -- Infectious diseases of the lung -- Essentials in critical care medicine -- Neoplastic disorders of the lung -- Preoperative and postoperative care -- Elements of renal structure and function -- Approach to the patient with renal disease -- Fluid and electrolyte disorders -- Glomerular diseases -- Major nonglomerular disorders -- Vascular disorders of the kidney -- Acute kidney injury -- Chronic renal failure -- Common clinical manifestations of gastrointestinal disease -- A: Abdominal pain -- B: Gastrointestinal hemorrhage -- C: Malabsorption -- D: Diarrha -- Endoscopic and imaging procedures -- Esophageal disorders -- Diseases of the stomach and duodenum -- Inflammatory bowel disease -- Neoplasms of the gastrointestinal tract -- Diseases of the pancreas --

Laboratory tests in liver disease -- Jaundice -- Acute and chronic hepatitis -- Fulminant hepatic failure -- Cirrhosis of the liver and its complications -- Disorders of the gallbladder and biliary tract -- Hematopoiesis and hematopoietic failure -- Clonal disorders of the hematopoietic stem cell -- Disorders of red blood cells -- Clinical disorders of neutrophils -- Disorders of lymphocytes -- Normal hemostasis -- Disorders of hemostasis: bleeding -- Disorders of hemostasis: thrombosis -- Cancer biology and etiologic factors -- Cancer epidemiology and cancer prevention -- Solid tumors -- Complications of cancer and cancer treatment -- Principles of cancer therapy -- Obesity -- Anorexia nervosa and bulimia nervosa -- Malnutrition, nutritional assessment, and nutritional support in adult patients -- Disorders of lipid metabolism -- Disorders of metals and metalloproteins -- Hypothalamic-pituitary axis -- Thyroid gland -- Adrenal gland -- Male reproductive endocrinology -- Diabetes mellitus -- Hypoglycemia -- Women's health topics -- A: Introduction -- B: Preventive health recommendations for women -- C: Health issues across the life course -- D: Special topics -- Men's health topics -- A: Benign prostatic hyperplasia -- B: Prostatitis -- C: Erectile dysfunction -- D: Carcinomas of men -- E: Benign scrotal diseases -- Normal physiology of bone and mineral homeostasis -- Disorders of serum minerals -- Metabolic bone diseases -- Osteoporosis -- Paget disease of bone -- Approach to the patient with rheumatic disease -- Rheumatoid arthritis -- Spondyloarthropathies -- Systemic lupus erythematosus -- Antiphospholipid antibody syndrome -- Systemic sclerosis (scleroderma) -- Idiopathic inflammatory myopathies -- Sjögrén syndrome --

Systemic vasculitis -- Crystal arthropathies -- Osteoarthritis -- Nonarticular soft tissue disorders -- Rheumatic manifestations of systemic disorders -- Organisms that infect humans -- Host defenses against infection -- Laboratory diagnosis of infectious diseases -- Antimicrobial therapy -- Fever and febrile syndromes -- Bacteremia and sepsis syndrome -- Infections of the nervous system -- Infections of the head and neck -- Infections of the lower respiratory tract -- Infections of the heart and blood vessels -- Skin and soft tissue infections -- Intra-abdominal abscess and peritonitis -- Infectious diarrhea -- Infections involving bones and joints -- Infections of the urinary tract -- Health care-associated infections -- Sexually transmitted infections -- Human immunodeficiency virus infection and acquired immunodeficiency syndrome -- Infections in the immunocompromised host -- Infectious diseases of travelers: protozoal and helminthic infections -- Bioterrorism -- Neurologic evaluation of the patient -- Disorders of consciousness -- Disorders of sleep -- Cortical syndromes -- Dementia and memory disturbances -- Major disorders of mood, thoughts, and behavior -- Disorders of thermal regulation -- Headache, neck pain, and other painful disorders -- Disorders of vision and hearing -- Dizziness and vertigo -- Disorders of the motor system -- Developmental and neurocutaneous disorders -- Cerebrovascular disease -- Traumatic brain injury and spinal cord injury -- Epilepsy -- Central nervous system tumors -- Infectious diseases of the nervous system -- Demyelinating and inflammatory disorders -- Neuromuscular diseases: disorders of the motor neuron and plexus and peripheral nerve disease -- Muscle diseases -- Neuromuscular junction disease -- The aging patient -- Palliative care -- Alcohol and substance abuse.