Hemostasis blood specimen management -- Hemostasis blood specimen quality -- Blood specimen collection : whole blood for aggregometry, plasma for coagulation testing -- Hematocrit adjustment for hemostasis specimens -- Therapeutic ranges and reference intervals -- A suggested hemostasis and coagulation test menu -- Bleeding disorders -- Coagulation factor inhibitors -- Von Willebrand disease -- Platelet function : aggregometry -- Fibrinolysis assays -- Disseminated intravascular coagulation (DIC) -- Anticoagulant therapy monitoring -- Lupus anticoagulant (LA) with follow-up assays -- Overview of the coagulation mechanism -- Coagulation mechanism controls -- Thrombophilia guidelines -- Why perform thrombophilia testing? -- Circumstantial thrombophilia risk factors -- Disease-related thrombophilia risk factors -- Circumstances that suggest a thrombophilia workup --

Complete thrombophilia laboratory test profile -- Selective thrombophilia test profile -- Lupus anticoagulant testing algorithms -- Lupus anticoagulant (LA) testing -- Anti-cardiolipin testing -- Antiphospholipid syndrome (APS) -- Risk of venous thromboembolism in acquired thrombophilia -- Prevalence of congenital thrombophilia -- Risk of venous thromboembolism in congenital thrombophilia -- Anticoagulant therapy monitoring guidelines -- Warfarin (Coumadin) -- Standard unfractionated heparin (UFH) -- Heparin-induced thrombocytopenia with thrombosis (HIT) -- Low molecular weight heparin (LMWH) : enoxaparin, tinzaparin -- Fondaparinux (Arixtra, pentasaccharide) -- Laboratory monitoring of LMWH and fondaparinux -- Direct thrombin inhibitors (DTIS) : argatroban and lepirudin -- Guidelines for the management of bleeding -- Hemorrhage and coagulopathy -- Tests used to establish presence of coagulopathies --

Interpreting PT and PTT results -- PTT mixing study -- Blood components -- Disseminated intravascular coagulation (DIC) profile -- Von Willebrand disease (VWD) -- VWD laboratory profile -- VWD follow-up testing -- VWD treatment options -- Scurvy -- Congenital single factor deficiencies (hemophilias) -- Factor VIII concentrates -- Factor IX concentrates -- Determining the plasma factor VIII or IX activity from the PTT -- Therapy options for factor inhibitors -- Activated prothrombin complex concentrates (APCCS) : FEIBA Fh, Autoplex -- Activated recombinant factor VII (Novoseven) -- Other congenital single-factor deficiencies -- Steps in using factor concentrates (summary) -- Guidelines for management of platelet disorders -- Platelet count ranges and thrombocytopenia -- Platelet diameter and morphology -- Qualitative platelet abnormalities -- Drugs with anti-platelet activity -- Platelet aggregometry -- Platelet concentrate therapy -- Treating uremia platelet dysfunction with red blood cells -- Thrombotic thrombocytopenic purpura (TTP) and VWF-cleaving protease assay.